Is Etrasimod safe while breastfeeding?

Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Etrasimod. The text below is quoted from that source — it is not our own verdict.

Summary of use during breastfeeding

No information is available on the use of etrasimod during breastfeeding. Etrasimod is 98% bound to plasma proteins and unlikely to reach the breastmilk in large amounts, but it has a slow clearance and long half-life and is potentially toxic to the breastfed infant. Some guidelines recommend avoiding etrasimod while breastfeeding because of the lack of information;[1] however, the manufacturer's labeling does not recommend against the use of etrasimod in breastfeeding. Until more data become available, etrasimod should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Effects on the breastfed infant

Relevant published information was not found as of the revision date.

Effects on milk supply

Relevant published information was not found as of the revision date.

Levels in milk

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

“No published information” means the studies do not exist yet — not that Etrasimod is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.

Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Etrasimod” (etrasimod). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.