Is Halothane safe while breastfeeding?
Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Halothane. The text below is quoted from that source — it is not our own verdict.
Summary of use during breastfeeding
Halothane is no longer available in the United States. There is no published experience with the therapeutic use of halothane as an anesthetic during breastfeeding, but trace amounts were found in the milk of a practicing anesthesiologist who had administered halothane in the operating room. Various recommendations have been made regarding breastfeeding after halothane anesthesia, from discarding the first pumping after recovery to discarding breastmilk for 24 to 48 hours after the surgical procedure.[1,2] Although withholding breastfeeding for 24 h is probably unnecessary, a short-acting anesthetic is preferred. In one study, breastfeeding before general anesthesia induction reduced requirements of sevoflurane and propofol compared to those of nursing mothers whose breastfeeding was withheld or nonnursing women.[3] It is possible that requirements for other anesthetic agents would be affected similarly.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. Foremilk samples taken on two occasions from a practicing anesthesiologist after administering halothane anesthesia in the operating room contained from 630 mcg/L to 2.1 mg/L (0.63-2.1 ppm) of halothane.[1] These values were higher than air samples from the operating room, but may be underestimates because of sampling techniques.
Infant Levels. Relevant published information was not found as of the revision date.
Alternatives LactMed lists
“No published information” means the studies do not exist yet — not that Halothane is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Halothane” (LM613). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.
