Is Natamycin safe while breastfeeding?

Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Natamycin. The text below is quoted from that source — it is not our own verdict.

Summary of use during breastfeeding

No information is available on the clinical use of natamycin during breastfeeding. However, other polyene antibiotics are poorly excreted into breastmilk and poorly absorbed by infants. Although unlikely, use of natamycin in the eye might disrupt the breastfed infant’s gastrointestinal flora. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 2 to 5 minutes, then remove the excess solution with an absorbent tissue. If a mother requires natamycin, it is not a reason to discontinue breastfeeding.

Effects on the breastfed infant

Relevant published information was not found as of the revision date.

Effects on milk supply

Relevant published information was not found as of the revision date.

Levels in milk

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

“No published information” means the studies do not exist yet — not that Natamycin is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.

Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Natamycin” (natamycin). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.