Is Polythiazide safe while breastfeeding?

Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Polythiazide. The text below is quoted from that source — it is not our own verdict.

Summary of use during breastfeeding

No information is available on the amount of polythiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over polythiazide.

Effects on the breastfed infant

Relevant published information was not found as of the revision date.

Effects on milk supply

Polythiazide 2 mg was given twice daily for 8 days beginning within 24 hours of delivery to suppress postpartum lactation. Patients also had breast binding for at least 10 days and fluid restriction. The authors reported that this technique was effective in 124 cases reviewed.[1] There are no data on the effects of diuretics on established lactation.

Levels in milk

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Alternatives LactMed lists

Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Polythiazide” (LM222). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.

Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.