Is Remimazolam safe while breastfeeding?
Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Remimazolam. The text below is quoted from that source — it is not our own verdict.
Summary of use during breastfeeding
Although the manufacturer recommends that nursing mothers pump and discard breast milk for 5 hours after a dose, anesthesia guidelines recommend that breastfeeding can resume as soon as the mother has recovered sufficiently from general anesthesia to nurse.[1,2] This strategy was employed at one center with no infant sedation or adverse effects.[3] When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
In one center, five patients delivered during remimazolam exposure. All neonates had 1-min Apgar scores ≥7 with no signs of sedation or breastfeeding difficulty.[3]
Levels in milk
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Alternatives LactMed lists
Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Remimazolam” (remimazolam). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.