Is Tirofiban safe while breastfeeding?
Here is what LactMed, the Drugs and Lactation Database published by the U.S. National Institute of Child Health and Human Development (NICHD), reports about Tirofiban. The text below is quoted from that source — it is not our own verdict.
Summary of use during breastfeeding
Tirofiban is an antiplatelet drug given by intravenous infusion. Its oral bioavailability has not been studied in humans, but is only 2.2% in rats. No information is available on the drug’s use during breastfeeding, but infants would not be expected to absorb clinically relevant amounts of the drug from milk. If a mother requires tirofiban, it is not a reason to discontinue breastfeeding, but monitor the infant for bruising or bleeding.
Effects on the breastfed infant
Relevant published information was not found as of the revision date.
Effects on milk supply
Relevant published information was not found as of the revision date.
Levels in milk
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
“No published information” means the studies do not exist yet — not that Tirofiban is known to be harmful, and not that it is known to be safe. Your prescriber or pharmacist can weigh your baby's age and whether a better-studied alternative would do the same job. Worth asking before stopping a medicine you need.
Source: Drugs and Lactation Database (LactMed), National Institute of Child Health and Human Development (NICHD), via NCBI Bookshelf, record “Tirofiban” (tirofiban). LactMed on NCBI Bookshelf. LactMed is a registered trademark of the U.S. Department of Health and Human Services.
Educational summary of an authoritative source — not medical advice. Never start, stop, or change a medicine while breastfeeding without confirming with your doctor.